Gemcitabine hydrochloride : status of preclinical studiesPETERS, Godefridus J; PLUNKETT, William.Seminars in oncology. 1995, Vol 22, Num 4, issn 0093-7754, 85 p., SUP11Serial Issue

Effects of antifolates on the binding of 5-fluoro-2'-deoxyuridine monophosphate to thymidylate synthaseVAN DER WILT, Clasina L; SMID, Kees; PETERS, Godefridus J et al.Biochemical pharmacology. 2002, Vol 64, Num 4, pp 669-675, issn 0006-2952, 7 p.Article

Steroids affect collateral sensitivity to gemcitabine of multidrug-resistant human lung cancer cellsBERGMAN, Andries M; PINEDO, Herbert M; PETERS, Godefridus J et al.European journal of pharmacology. 2001, Vol 416, Num 1-2, pp 19-24, issn 0014-2999Article

Synthesis and in vitro cytotoxicity of long chain 2-amino alcohols and 1,2-diaminesMARKIDIS, Theodoros; PADRON, José M; MARTIN, Victor S et al.Anticancer research. 2001, Vol 21, Num 4A, pp 2835-2839, issn 0250-7005Article

Irinotecan-induced cytotoxicity to colon cancer cells in vitro is stimulated by pre-incubation with trifluorothymidineTEMMINK, Olaf H; HOEBE, Eveline K; FUKUSHIMA, Masakazu et al.European journal of cancer (1990). 2007, Vol 43, Num 1, pp 175-183, issn 0959-8049, 9 p.Article

Low folate conditions may enhance the interaction of trifluorothymidine with antifolates in colon cancer cellsTEMMINK, Olaf H; HOOGELAND, Marco F. M; FUKUSHIMA, Masakazu et al.Cancer chemotherapy and pharmacology. 2006, Vol 57, Num 2, pp 171-179, issn 0344-5704, 9 p.Article

An expedient assay for determination of gemcitabine and its metabolite in human plasma using isocratic ion-pair reversed-phase high-performance liquid chromatographyWANG, Ling-Zhi; GOH, Boon-Cher; LEE, How-Sung et al.Therapeutic drug monitoring. 2003, Vol 25, Num 5, pp 552-557, issn 0163-4356, 6 p.Article

Gemcitabine : a modulator of intracellular nucleotide and deoxynucleotide metabolismHEINEMANN, V; SCHULZ, L; ISSELS, R. D et al.Seminars in oncology. 1995, Vol 22, Num 4, pp 11-18, issn 0093-7754, SUP11Article

Molecular mechanisms underlying the role of microRNAs (miRNAs) in anticancer drug resistance and implications for clinical practiceGIOVANNETTI, Elisa; EROZENCI, Ayse; SMIT, Jorn et al.Critical reviews in oncology/hematology. 2012, Vol 81, Num 2, pp 103-122, issn 1040-8428, 20 p.Article

Consequences of 2',2'-difluorodeoxycytidine (gemcitabine) on replicative DNA synthesis in intact HL-60 cellsROSS, D. D; CUDDY, D. P.Seminars in oncology. 1995, Vol 22, Num 4, pp 26-34, issn 0093-7754, SUP11Article

Radiosensitization of human tumor cells by gemcitabine in vitroSHEWACH, D. S; LAWRENCE, T. S.Seminars in oncology. 1995, Vol 22, Num 4, pp 68-71, issn 0093-7754, SUP11Article

Modulation of folate uptake in cultured human colon adenocarcinoma Caco-2 cells by dietary compoundsLEMOS, Clara; PETERS, Godefridus J; JANSEN, Gerrit et al.European journal of nutrition (Print). 2007, Vol 46, Num 6, pp 329-336, issn 1436-6207, 8 p.Article

Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignanciesTEMMINK, Olaf H; EMURA, Tomohiro; DE BRUIN, Michiel et al.Cancer science. 2007, Vol 98, Num 6, pp 779-789, issn 1347-9032, 11 p.Article

Synthesis and in vitro cytotoxicity of novel long chain busulphan analoguesKOKOTOS, George; CONSTANTINOU-KOKOTOU, Violetta; PADRON, José M et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 6, pp 861-863, issn 0960-894XArticle

Evaluation of the cytotoxic activity of gemcitabine in primary cultures of tumor cells from patients with hematologic or solid tumorsCSOKA, K; LILLIEMARK, J; LARSSON, R et al.Seminars in oncology. 1995, Vol 22, Num 4, pp 47-53, issn 0093-7754, SUP11Article

Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiationCASTRO KREDER, Natasja; VAN BREED, Chris; PETERS, Godefridus J et al.Oncology reports. 2002, Vol 9, Num 1, pp 141-144, issn 1021-335XArticle

Molecular mechanism underlying the synergistic interaction between trifluorothymidine and the epidermal growth factor receptor inhibitor erlotinib in human colorectal cancer cell linesBIJNSDORP, Irene V; KRUYT, Frank A. E; FUKUSHIMA, Masakazu et al.Cancer science. 2010, Vol 101, Num 2, pp 440-446, issn 1347-9032, 7 p.Article

Gemcitabine chemoresistance in pancreatic cancer: Molecular mechanisms and potential solutionsANDERSSON, Roland; AHO, Ursula; NILSSON, Bo I et al.Scandinavian journal of gastroenterology. 2009, Vol 44, Num 7, pp 782-786, issn 0036-5521, 5 p.Article

Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpressionSIGMOND, Jennifer; BACKUS, Harold H. J; WOUTERS, Dorine et al.Biochemical pharmacology. 2003, Vol 66, Num 3, pp 431-438, issn 0006-2952, 8 p.Article

Gemcitabine : metabolism, mechanisms of action, and self-potentiationPLUNKETT, W; PENG HUANG; YI-ZHENG XU et al.Seminars in oncology. 1995, Vol 22, Num 4, pp 3-10, issn 0093-7754, SUP11Article

Folates provoke cellular efflux and drug resistance of substrates of the multidrug resistance protein 1 (MRP1)HOOIJBERG, Jan Hendrik; JANSEN, Gerrit; KATHMANN, Ietje et al.Cancer chemotherapy and pharmacology. 2014, Vol 73, Num 5, pp 911-917, issn 0344-5704, 7 p.Article

Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360)PETERS, Godefridus J; SMID, Kees; LAK SHIN JEONG et al.Investigational new drugs. 2013, Vol 31, Num 6, pp 1444-1457, issn 0167-6997, 14 p.Article

N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferationGRANCHI, Carlotta; ROY, Sarabindu; LUCACCHINI, Antonio et al.European journal of medicinal chemistry. 2011, Vol 46, Num 11, pp 5398-5407, issn 0223-5234, 10 p.Article

Effects of gemcitabine on cis-platinum-DNA adduct formation and repair in a panel of gemcitabine and cisplatin-sensitive or -resistant human ovarian cancer cell linesPETERS, Godefridus J; VAN MOORSEL, Catharina J. A; PINEDO, Herbert M et al.International journal of oncology. 2006, Vol 28, Num 1, pp 237-244, issn 1019-6439, 8 p.Article

Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemiaSTAM, Ronald W; DEN BOER, Monique L; MEIJERINK, Jules P. P et al.Blood. 2003, Vol 101, Num 4, pp 1270-1276, issn 0006-4971, 7 p.Article